GLP-1 receptor agonists in research
GLP-1 (glucagon-like peptide-1) receptor agonists are a class of peptides that mimic the incretin hormone GLP-1. In research settings, these peptides are studied for their effects on glucose metabolism, insulin secretion, and related metabolic pathways in vitro.
Semaglutide
Semaglutide is a GLP-1 receptor agonist with a modified structure that extends its half-life. It features a C-18 fatty acid chain conjugated via a linker to position 26, which promotes albumin binding. Molecular weight: approximately 4113.58 Da. Available as a lyophilized powder for in vitro research applications.
Tirzepatide
Tirzepatide is a dual GLP-1/GIP (glucose-dependent insulinotropic polypeptide) receptor agonist. This dual mechanism distinguishes it from single-target GLP-1 agonists in metabolic pathway studies. Molecular weight: approximately 4813.45 Da. Available as a lyophilized powder.
RT-3
RT-3 is a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. This multi-receptor activity makes it a unique research tool for studying the interplay between these three metabolic signaling pathways. Available as a lyophilized powder for in vitro research.